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RESOF L - Ledipasvir 90 mg and Sofosbuvir 400 mg Tablets

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RESOF L - Ledipasvir 90 mg and Sofosbuvir 400 mg Tablets

Brand name: Resof L
Contents : Ledipasvir and Sofosbuvir
Marketed by: Dr. Reddy's Laboratories Limited
Form: Tablets
Strength: 90 mg Ledipasvir and
400 mg Sofosbuvir
Packing: Pack of 28 tablets

Availability: In stock



What is Resof L ?

Resof L is a fixed-dose combination tablet that contains Ledipasvir (90mg) and Sofosbuvir (400mg) for oral administration to treat patients with Hepatitis C virus. Resof L is manufactured by Dr. Reddy's and comes in a packed plastic bottle containing 28 tablets. Buy Resof L online from Emedkit online from anywhere in the world, especially in countries like USA, Russia, China, Peru and Romania.

Sofosbuvir is a nucleotide analog that is used in combination with other drugs for the treatment of patients with Hepatitis C Virus (HCV) infection. This drug has been marketed since the year 2013. Compared to previously available treatments, sofosbuvir-based line of treatment provides a higher cure rate, fewer side effects, and a two- to four-fold reduction in the duration of therapy. Sofosbuvir allows most patients to be treated successfully without the use of peginterferon, an injectable drug that has severe side effects which was a key component of older drug combinations for the treatment of HCV.

Sofosbuvir inhibits the RNA polymerase that the Hepatitis C virus uses to replicate its RNA. It was discovered at Pharmasset and developed by Gilead Sciences.

Resof is a prescription medicine that can be purchased by a patient only on a valid prescription from a healthcare professional. Do not share this hepatitis medicine with others because it can cause serious side effects and needs constant monitoring by the doctor.

Resof L Tablet prescribed in case of:

Buy Resof L online from Emedkit (Ledipasvir 90mg/ Sofosbuvir 400mg), that is an extremely effective HCV drug that is used to treat chronic hepatitis C virus, which is an ongoing viral infection that damages the liver. This drug is used in a combination with another drug, to prevent the spread of HCV in the body.

How Resof L Tablet Works?

Resof L is a direct-acting antiviral (DAA) medication. DAAs are a group of medications that functions to directly block the ability of the hepatitis C virus to make its own copies.

Resof L is a combination drug of two direct-acting antiviral drugs that work by targeting different steps of the hepatitis C virus (HCV) life cycle. One is Sofosbuvir, which is a nucleotide polymerase inhibitor. The other is Ledipasvir, which is an NS5A inhibitor. Sofosbuvir interferes with the reproduction of the virus’s genetic material, stopping the production of new Hep C virus. Ledipasvir works by interfering with a protein that is required to complete the Hep C virus life cycle in the liver cell.

Drug Interactions of RESOF L:

Most Drug Interactions With Ledipasvir/Sofosbuvir Involve Pgp-Inducers Rifampicin. This drug is known to develop resistance in the blood stream for Ledipapsvir/ Sofosbuvir which may result in reduced therapeutic effects with time.

Contraindications of RESOF L TABLET:

When Used In Combination With other drugs such as Peginterferon Alfa/Ribavirin Or Ribavirin separately, all Contraindications towards Peginterferon Alfa and/or Ribavirin also apply to Ledipasvir/Sofosbuvir Combination Therapy.


Side Effects of Resof L Tablets:

While taking Resof L hepatitis medicine, it’s necessary to be aware of the changes that may take place in your body and how you may feel. This medicine may cause some side effects, therefore it is essential to keep a note of them. Side effects of Sofosbuvir/Ledipasvir range from mild to severe and the risk of experiencing side effects may vary from person to person.:


Serious Side Effects of Resof L Tablets:

  • Chest pain or discomfort 
  • Slow or irregular heartbeat
  • Shortness of breath
  • Dizziness or fainting
  • Unconsciousness
  • Light headedness
  • Unusual tiredness etc.


Common Side Effects of Resof L Tablets :

  • Fatigue  
  • Rash
  • Diarrhoea
  • Headache 
  • Tiredness
  • Feeling sad or empty 
  • Lack of appetite 
  • Loss of interest or pleasure
  • Trouble sleeping
  • Irritability
  • Lack or loss of strength
  • Trouble concentrating  
  • Discouragement etc.

This is not the complete list of side effects with Ledipasvir 90 mg/Sofosbuvir 400 mg. Please discuss with your healthcare provider or doctor about any side effect that you make experience or any effect that persists longer than it should.

Special Precautions for RESOF L:

Bradycardia with Amiodarone Co-administration: Serious Symptomatic Bradycardia may occur in patients consuming Amiodarone and Sofosbuvir in combination with another Direct Acting Antiviral (DAA), particularly in patients also receiving Beta Blockers, or those with underlying Cardiac Co-morbidities and/ or Advanced Liver Disease.

Co-administration of Amiodarone with Sofosbuvir in combination with another DAA is not recommended. In patients without alternative feasible treatment options, Cardiac Monitoring is recommended.

Pregnancy: Ribavirin can cause birth defects and fetal death and animal studies have shown interferon have abortifacient effects therefore it is essential to avoid pregnancy in female patients and female partners of the male patients. Patients must have a negative pregnancy test prior to initiating therapy, they should use at least 2 Effective methods of contraception and have monthly Pregnancy Tests.


Store Resof L away from moisture and heat. Store at room temperature or below 30°C (86°F)



Resof L is powerful in combination with other drugs against hepatitis C. It employed when the patient has a severe allergic reaction to ribavirin, interferon since it can be used independently of these drugs. Buy Resof L tablet online by company Dr. Reddy’s Laboratories from Emedkit.

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