Sofosbuvir is a nucleotide analog used in combination with other drugs for the treatment of Hepatitis C virus (HCV) infection. It has been marketed since 2013. Compared to previous treatments, sofosbuvir-based regimens provide a higher cure rate, fewer side effects, and a two- to four-fold reduced duration of therapy. Sofosbuvir allows most patients to be treated successfully without the use of peginterferon,an injectable drug with severe side effects that is a key component of older drug combinations for the treatment of HCV.
Sofosbuvir inhibits the RNA polymerase that the Hepatitis C virus uses to replicate its RNA. It was discovered at Pharmasset and developed by Gilead Sciences.
What is Resof L Tablet ?
Resof L is a fixed-dose combination tablet containing Ledipasvir and Sofosbuvir for oral administration. Resof L manufactured by Dr. Reddy's comes in a pack of 28 tablets. It is a prescription medicine that can be purchased by a patient only against a valid prescription of a healthcare professional. Do not share this hepatitis medicine with others because it can cause serious side effects to people until the condition is not monitored by a pharmacist.
When is Resof L Tablet prescribed ?
Resof L (Ledipasvir/Sofosbuvir) is a very effective HCV drug that is used to treat chronic hepatitis C (an ongoing viral infection that damages the liver). This drug is used in a combination with another drug, to prevent the spread of HCV throughout the body.
How Does Resof L (Ledipasvir / Sofosbuvir) Tablet Work ?
Resof L is a direct-acting antiviral (DAA) medication. DAAs are a group of medications that directly block the ability of the hepatitis C virus to make copies of itself.
It is a combination of two direct-acting antiviral drugs that target different steps of the hepatitis C virus (HCV) life cycle. One is Sofosbuvir, which is a nucleotide polymerase inhibitor, and the other is Ledipasvir, which is an NS5A inhibitor. Sofosbuvir interferes with the reproduction of the virus’s genetic material, stopping the production of new Hep C virus. Ledipasvir works by interfering with a protein needed to complete the Hep C virus life cycle in the liver cell.
What are the adverse effects of Resof L Tablets ?
When you take Resof L hepatitis medicine, it’s important to be aware of changes in your body and how you feel. This medicine can cause some side effects. Side effects can range from mild to severe and the risk of getting side effects varies from person to person. The following is a list of possible side-effects that may occur in medicines that contain Sofosbuvir/Ledipasvir :
Common Side Effects of Resof L Tablets : Fatigue ; Headache ; Diarrhea ; Lack of appetite ; Tiredness ; Feeling sad or empty ; Rash ; Trouble sleeping ; Lack or loss of strength ; Trouble concentrating ; Loss of interest or pleasure ; Irritability ; Discouragement etc.
Serious Side Effects of Resof L Tablets : Chest pain or discomfort ; Shortness of breath ; slow or irregular heartbeat ; Unconsciousness ; Lightheadedness ; Dizziness or fainting ; Unusual tiredness etc.
These are not all the side effects with Ledipasvir 90 mg/Sofosbuvir 400 mg. Tell your healthcare provider about any side effect that bothers you or does not go away.
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