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Entecavir (Entekor-0.5mg) Tablets

Hepbest 25mg Tenofovir Alafenamide Tablets

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Quick Overview

Pharmaceutical form


Film-coated tablet.


A white to off-white, film-coated, round, biconvex tablet debossed with M on one side of the tablet and TFI on the other side.


Posology and method of administration


Therapy should be initiated by a physician experienced in the management of chronic hepatitis B.

Availability: In stock

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Details

Posology

Adults and adolescents (aged 12 years and older with body weight at least 35 kg): one tablet once daily.

Treatment discontinuation:

Treatment discontinuation may be considered as follows (see section 4.4):

• In HBeAgpositive patients without cirrhosis, treatment should be administered for at least 612 months after HBe seroconversion (HBeAg loss and HBV DNA loss with antiHBe detection) is confirmed or until HBs seroconversion or until there is loss of efficacy (see section 4.4). Regular reassessment is recommended after treatment discontinuation to detect virological relapse.

• In HBeAgnegative patients without cirrhosis, treatment should be administered at least until HBs seroconversion or until there is evidence of loss of efficacy. With prolonged treatment for more than 2 years, regular reassessment is recommended to confirm that continuing the selected therapy remains appropriate for the patient.

Missed dose: If a dose is missed and less than 18 hours have passed from the time it is usually taken, the patient should take Tenofovir Alafenamide tablets 25 mg as soon as possible and then resume their normal dosing schedule. If more than 18 hours have passed from the time it is usually taken, the patient should not take the missed dose and should simply resume the normal dosing schedule.

If the patient vomits within 1 hour of taking Tenofovir Alafenamide tablets 25 mg, the patient should take another tablet. If the patient vomits more than 1 hour after taking Tenofovir Alafenamide tablets 25 mg, the patient does not need to take another tablet.

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