Bortenat- 3.5Mg Injection
Bortenat 3.5mg injection is used for treating some particular types of cancers such as multiple myeloma and mantle cell lymphoma. This is an antineoplastic drug, therefore it is used in chemotherapy. The drug works by blocking the function of some types of protein that is present in the cancer cell, which ultimately destroys it. The active ingredient in Bortenat is Bortezomib. This 3.5 mg injection has been manufactured by Natco Pharma Ltd. And is available at emedkit in countries like USA, Russia, China, Peru and Romania.
Indication for use of Bortenat- 3.5Mg Injection:
Bortenat 3.5mg Injection is indicated for the treatment of the patients with:
Uses of Bortenat- 3.5Mg Injection:
This medication is a chemotherapy drug for cancer that is used for treating some types of tumours. It works by blockings certain proteins which help in slowing down the growth and the spread of cancer within the body. It is used in case of the following types of cancer:
Bortenat is available at Emedkit a leading trader, exporter and supplier of medicines.
Dosage for Bortenat- 3.5Mg Injection
Bortenat is administered as a 3- 5 sec bolus IV injection in a combination with oral melphalan and oral pednisone for nine cycles of 6- week treatment to previously untreated Multiple Myeloma.
In the cycles of 1- 4 of Bortenat is administered twice weekly (on days 1, 4, 8, 11, 22, 25, 29 and 32). In the cycles of 5- 9 of Bortenat is administered once weekly (on days 1, 8, 22 and 29).
Bortenat 3.5 mg injection is administered in the form of a 3- 5 sec IV bolus injection through a peripheral or central IV catheter which is further followed by a flush with 0.9% of sodium chloride solution for the injection.
Note: There needs to be at least 72 hours gap between the consecutive doses of Bortenat.
Contraindications of Bortenat 3.5Mg Injection:
The following are the contradictions of Bortenat 3.5mg injection:
Do not use Bortenat if you are pregnant as it is known to cause harm to the unborn child.
Bortenat can reduce the count of blood cells in the body which help your body in fighting infections and helping your blood clot faster. Due to this contradiction it is advised to get your blood tested on a frequent basis. These can also determine the course of your cancer treatments which can be delayed based on the results of these tests.
It is possible to experience a gradual change in the mental state or one can also experience decreased vision, speech and walking difficulties, impaired thinking or reactions. It is advised to inform the doctor for immediate medical attention.
There can be a possibility of becoming dehydrated if you experience vomiting or diarrhoea with Bortenat, therefore it is advised to stay hydrated.
This medication can cause blurred vision; therefore it is suggested to be careful while driving or doing anything that requires alertness and clarity of sight. Also, the pharmacokinetics of Bortenat is not influenced by the degree of renal impairment. Thus, adjustment of doses of Bortenat 3.5 mg injection is not necessary for patients having renal insufficiency.
As the dialysis can reduce the concentration levels of Bortenat, the drug should be administered after the procedure of dialysis has been done.
Patients who experience mild hepatic impairment need not require any adjustment for the starting dose and must be treated with the recommended Bortenat dose. Patients having a moderate or severe hepatic impairment should be started with Bortenat at a reduced dose of 0.7 mg/m2/ injection during the 1st cycle of the treatment and a subsequent advancement to 1mg/ m2, or a further reduction of 0.5mg/ m2 which may be regulated as per the tolerance of the patient.
The safety and effectiveness of Bortenat 3.5 mg injection has not been established in children.
Instructions for the Use of 3.5Mg Injection:
Note: The above discussed instructions are intended to familiarize the patients with the effect of the drug and are not recommended for self- treatment.
Some Less Serious Side effects are:
Some Side effects are:
Very serious side effects are:
An allergic reaction to this drug is very unlikely, but if one occurs, then it is advised to get immediate medical help. Symptoms of Allergic Reactions:
Note: This is not a complete list of possible side effects. If any of the above mentioned side effects persist or worsen, inform your doctor immediately. Remember this medication has been prescribed to you by the doctor as he or she has judged that the benefit of the drug to you is greater than the risk of the side effects.
- Nerve sensation problems (e.g., peripheral neuropathy)
- Heart diseases
- Low blood pressure
- loss of body fluids (dehydration)
- liver disease
- severe kidney disease
- certain viral infection (herpes, shingles)
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